VALUE OF ED50 TESTING IN ASSESSING HAZARDS OF ACUTE POISONING BY CARBAMATES AND ORGANOPHOSPHATES
نویسندگان
چکیده
منابع مشابه
Value of ED50 testing in assessing hazards of acute poisoning by carbamates and organophosphates.
It is shown from the kinetics of inhibition of cholinesterase by N-methylcarbamates and organo-phosphates that the LD50 dose is likely to be a much greater multiple of the dose causing signs of poisoning in 50%-of the animals (the ED50) for the carbamates than for the organophosphates. The expected difference was demonstrated by a comparison of the LD50s and ED50s, intravenous and intramuscular...
متن کاملThe use of serial measurement of plasma cholinesterase in the management of acute poisoning with organophosphates and carbamates.
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ژورنال
عنوان ژورنال: Occupational and Environmental Medicine
سال: 1965
ISSN: 1351-0711
DOI: 10.1136/oem.22.4.317